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ENZOLIFE SCIENCES

SCREEN-WELL Libraries

SCREEN-WELL Libraries

Accelerate your drug discovery with SCREEN-WELL pre-plated compound libraries. Curated collections of bioactive compounds ready for high-throughput and phenotypic screening — saving you months of compound sourcing and plate preparation.

SCREEN-WELL at a Glance

10+
Curated Libraries
5,000+
Unique Compounds
96/384
Well Plate Formats
Ready
To Screen

Available Libraries

Each library is expertly curated, plated in DMSO, and ready for screening

FDA-Approved Drug Library

Collection of FDA-approved drugs for drug repurposing and phenotypic screening. Covers diverse therapeutic categories including anti-infectives, anti-inflammatories, cardiovascular, CNS, and oncology drugs.

Kinase Inhibitor Library

Comprehensive collection of kinase inhibitors targeting major kinase families — tyrosine kinases, serine/threonine kinases, lipid kinases. Includes clinical-stage and approved inhibitors.

Epigenetics Library

HDAC inhibitors, HAT inhibitors, methyltransferase inhibitors, bromodomain ligands, and other epigenetic modulators. The definitive collection for chromatin biology research.

Autophagy Library

Compounds that modulate autophagy pathways — inducers and inhibitors of macroautophagy, mitophagy, and chaperone-mediated autophagy. Tools for studying this critical cellular process.

ICCB Known Bioactives Library

Large, diverse collection of well-characterized bioactive compounds with known mechanisms of action. Ideal for unbiased phenotypic screens and target identification.

Natural Products Library

Curated collection of natural product compounds from plant, marine, and microbial sources. Rich source of chemical diversity for lead discovery and SAR studies.

Nuclear Receptor Ligand Library

Agonists and antagonists for nuclear hormone receptors — estrogen, androgen, glucocorticoid, PPAR, RXR, and others. Essential for endocrine and metabolic research.

Proteasome Inhibitor Library

Compounds targeting the ubiquitin-proteasome pathway — proteasome inhibitors, DUB inhibitors, and E3 ligase modulators for protein homeostasis research.

Apoptosis Library

Modulators of programmed cell death — caspase activators/inhibitors, Bcl-2 family modulators, death receptor agonists, and mitochondrial pathway regulators.

Why Choose SCREEN-WELL?

Screening Support

Our scientists can help you select the right library and optimize your screening workflow:

  • Library Selection Consultation — Which library best matches your target biology and screening format?
  • Assay Compatibility — Guidance on adapting your assay for plate-based compound screening
  • Data Analysis Support — Assistance with hit identification, dose-response confirmation, and SAR analysis
  • Custom Library Assembly — Need a focused subset? We can create custom plates from our compound inventory
  • Counter-Screening — Selectivity profiling against related targets using our enzyme and cell-based assay portfolio

Technical Specifications

  • Format: 96-well or 384-well polypropylene microplates
  • Solvent: DMSO (10 mM stock concentration, unless otherwise specified)
  • Storage: -20C, desiccated, protected from light
  • Stability: Minimum 12 months when stored properly
  • Shipping: Ambient temperature on dry ice, worldwide delivery

Researcher Feedback

SCREEN-WELL libraries saved us months of compound sourcing. We identified three novel HDAC inhibitor chemotypes in our first screen using the Epigenetics Library.

Dr. James Park

The compound quality and plate uniformity are excellent. We have been using the FDA-Approved Drug Library for repurposing screens in rare diseases with great success.

Dr. Elena Vasquez

The documentation is outstanding — plate maps, structures, known targets, and references for every compound. It makes hit follow-up straightforward.

Dr. Thomas Chen

SCREEN-WELL libraries saved us months of compound sourcing. We identified three novel HDAC inhibitor chemotypes in our first screen using the Epigenetics Library.

Dr. James Park

The compound quality and plate uniformity are excellent. We have been using the FDA-Approved Drug Library for repurposing screens in rare diseases with great success.

Dr. Elena Vasquez

The documentation is outstanding — plate maps, structures, known targets, and references for every compound. It makes hit follow-up straightforward.

Dr. Thomas Chen

Start Screening Today

Request a quote or speak with our screening specialists to find the right SCREEN-WELL library for your drug discovery program.

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