Drug Repurposing
Drug Repurposing
Discover new therapeutic applications for existing drugs with curated FDA-approved compound libraries, phenotypic screening assays, and mechanism profiling tools.
New Life for Proven Molecules
Drug repurposing offers a faster, lower-risk path to new therapies by identifying novel indications for drugs with established safety profiles. Enzo Life Sciences provides the screening libraries and assay platforms that enable systematic repurposing discovery — from curated FDA-approved drug collections for phenotypic screening to comprehensive mechanism-of-action profiling tools for validating new therapeutic hypotheses.
FDA-Approved Drug Libraries
SCREEN-WELL FDA-Approved Drug Library featuring clinically used compounds with established safety and pharmacokinetic profiles. Pre-plated in microplate formats with detailed mechanism-of-action annotations for rapid phenotypic screening across new disease indications.
Phenotypic Screening
Cell-based assay platforms for disease-relevant phenotypic screening of repurposing candidates. Proliferation, apoptosis, autophagy, and inflammation readouts enable identification of compounds with therapeutic activity in new disease contexts.
Mechanism Profiling
Pathway analysis tools and target deconvolution reagents to understand how repurposed drugs act in new indications. Signal transduction, epigenetic, and cell death pathway profiling tools validate mechanistic hypotheses for regulatory support.
Combination Screening
Synergy assessment tools for evaluating drug combinations in repurposing programs. Dose-matrix assays and isobologram analysis platforms identify synergistic combinations that enhance efficacy while leveraging established safety data.
Drug Repurposing — By the Numbers
Start Your Repurposing Screen
Explore our curated product selection or contact our scientific support team for personalized recommendations.