In Vitro Toxicology
In Vitro Toxicology
Identify toxic liabilities early with comprehensive in vitro cytotoxicity assays, oxidative stress panels, and organ-specific toxicity detection platforms.
Early Safety Screening Saves Development Costs
In vitro toxicology is a critical gatekeeper in drug development, enabling early identification of cytotoxic, genotoxic, and organ-specific toxic liabilities before costly in vivo studies. Enzo Life Sciences provides a complete suite of in vitro safety screening tools — from general cytotoxicity assays to specialized hepatotoxicity, cardiotoxicity, and nephrotoxicity panels — helping you de-risk your pipeline early and reduce late-stage attrition.
Cytotoxicity Assays
Cell viability and cytotoxicity detection kits using MTT, resazurin, LDH release, and ATP-based readouts. Our validated platforms support high-throughput screening in 96- and 384-well formats with excellent Z’-factor performance for safety screening cascades.
Oxidative Stress Panels
ROS detection probes, glutathione assays, and lipid peroxidation markers for oxidative stress-mediated toxicity. SENTINEL oxidative stress platform provides a comprehensive panel for assessing mitochondrial dysfunction, oxidative damage, and antioxidant depletion.
Apoptosis & Cell Death
Mechanistic cell death assays distinguishing apoptosis, necrosis, autophagy, and ferroptosis. APOPCYTO detection kits with Annexin V conjugates and caspase substrates enable precise characterization of cytotoxic mechanisms for regulatory submissions.
Organ-Specific Toxicity
Specialized biomarker panels for hepatotoxicity (ALT, AST, bile acids), cardiotoxicity (troponin, BNP), and nephrotoxicity (KIM-1, NGAL) assessment. ELISA-based quantification of tissue injury biomarkers from in vitro culture systems.
In Vitro Toxicology — By the Numbers
De-Risk Your Pipeline Early
Explore our curated product selection or contact our scientific support team for personalized recommendations.