DNA Regulation & Transcription
DNA Regulation & Transcription
DNA damage detection, transcription factor analysis, and gene regulation tools — from genomic integrity surveillance to transcriptional control mechanisms.
Understanding Gene Regulation & Genomic Integrity
The regulation of DNA integrity and transcription lies at the heart of cell biology, disease, and therapeutic development. From DNA damage response and repair pathways to transcription factor activation and chromatin remodeling, these processes govern cell fate, proliferation, and survival. Enzo Life Sciences supports researchers studying gene regulation with validated DNA damage detection kits, transcription factor activity assays, topoisomerase inhibitors, and tools for analyzing the molecular machinery that reads, repairs, and regulates our genome.
DNA Damage Detection
Quantify DNA damage with our validated 8-OHdG ELISA (the gold standard for oxidative DNA damage), gamma-H2AX immunofluorescence kits, comet assay reagents, and CPD/6-4PP photoproduct detection assays. Support genotoxicity screening, radiation biology, and DNA repair studies.
Transcription Factor Assays
Measure transcription factor DNA-binding activity with colorimetric and chemiluminescent ELISA-based kits for NF-κB, AP-1, p53, HIF-1α, STAT3, and other key transcriptional regulators. No radioactivity required — simple plate-based format for high-throughput analysis.
DNA Repair Pathway Tools
Antibodies and activity assays for base excision repair (OGG1, APE1), nucleotide excision repair (XPC, ERCC1), mismatch repair (MLH1, MSH2), and double-strand break repair (BRCA1, Rad51) pathways. Study repair deficiency in cancer and aging models.
Topoisomerase & Transcription Inhibitors
Small molecule libraries and individual compounds targeting topoisomerase I/II, RNA polymerase, and transcriptional CDKs. SCREEN-WELL compound sets with detailed mechanism-of-action annotations for functional studies and drug screening applications.
DNA Regulation & Transcription — By the Numbers
Explore DNA regulation tools
Explore our curated product selection for this research area or contact our scientific support team for personalized recommendations.