Cell Death
Cell Death
The most comprehensive cell death detection portfolio in the industry — apoptosis, autophagy, necroptosis, ferroptosis, and pyroptosis tools for mechanistic and therapeutic research.
Detecting Every Mode of Cell Death
Cell death is a fundamental biological process with profound implications for cancer, neurodegeneration, infection, and inflammatory disease. Beyond classical apoptosis, researchers now recognize diverse regulated cell death pathways including autophagy, necroptosis, ferroptosis, and pyroptosis — each with distinct molecular mechanisms and therapeutic relevance. Enzo Life Sciences has built the industry's most comprehensive cell death detection portfolio, with validated kits and reagents covering every major cell death pathway from initial signaling events through terminal execution.
Apoptosis Detection
Gold-standard Annexin V conjugates (FITC, PE, APC, and biotin), caspase activity assays (Caspase-3/7, -8, -9), TUNEL kits, and mitochondrial membrane potential probes. Our APOPCYTO apoptosis detection platform enables multiparameter analysis of intrinsic and extrinsic apoptotic pathways by flow cytometry, microscopy, and plate reader.
Autophagy Detection
Our proprietary CYTO-ID Autophagy Detection Kit is the most widely cited fluorescent autophagy assay globally. Selectively labels autophagic vacuoles in live cells without genetic manipulation. Compatible with flow cytometry, fluorescence microscopy, and microplate readers for high-throughput autophagy screening.
Necroptosis & Pyroptosis
Detect programmed necrosis pathways with MLKL phosphorylation antibodies, RIPK1/RIPK3 activity assays, and gasdermin D cleavage detection kits. Our reagents support mechanistic studies of inflammatory cell death in infection, autoimmunity, and sterile inflammation models.
Ferroptosis & Lipid Peroxidation
Monitor iron-dependent cell death with lipid peroxidation sensors, GPX4 activity assays, and iron quantification kits. Our SENTINEL oxidative stress platform detects MDA, 4-HNE, and F2-isoprostanes — key biomarkers of the lipid peroxidation cascade driving ferroptotic cell death.
Cell Death — By the Numbers
Find your cell death assay
Explore our curated product selection for this research area or contact our scientific support team for personalized recommendations.